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Publications WG Grütz

Here you will find a selection of publications on cytokine regulation by the WG Grütz.

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Selected publications

  • Sabat R, Wolk K, Wallace E, Grutz G. 2007. Biology of Interleukin-10: Transworld Research Network. 107-26 pp.
  • Tykocinski LO, Hajkova P, Chang HD, Stamm T, Sozeri O, Lohning M, Hu-Li J, Niesner U, Kreher S, Friedrich B, Pannetier C, Grutz G, Walter J, Paul WE, Radbruch A. 2005. A critical control element for interleukin-4 memory expression in T helper lymphocytes. J Biol Chem 280: 28177-85
  • Grutz G. 2005. New insights into the molecular mechanism of interleukin-10-mediated immunosuppression. J Leukoc Biol 77: 3-15
  • Wolk K, Grutz G, Witte K, Volk HD, Sabat R. 2005. The expression of legumain, an asparaginyl endopeptidase that controls antigen processing, is reduced in endotoxin-tolerant monocytes. Genes Immun
  • Hoflich C, Sabat R, Rosseau S, Temmesfeld B, Slevogt H, Docke WD, Grutz G, Meisel C, Halle E, Gobel UB, Volk HD, Suttorp N. 2004. Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood 103: 673-5
  • Schroder M, Kroeger KM, Volk HD, Eidne KA, Grutz G. 2004. Preassociation of nonactivated STAT3 molecules demonstrated in living cells using bioluminescence resonance energy transfer: a new model of STAT activation? J Leukoc Biol 75: 792-7
  • Tse E, Smith AJ, Hunt S, Lavenir I, Forster A, Warren AJ, Grutz G, Foroni L, Carlton MB, Colledge WH, Boehm T, Rabbitts TH. 2004. Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice. Mol Cell Biol 24: 2063-73
  • Sawitzki B, Kieselbach B, Fisser M, Meisel C, Vogt K, Gaestel M, Lehmann M, Risch K, Grutz G, Volk HD. 2004. IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness. J Am Soc Nephrol 15: 695-703
  • Jung M, Sabat R, Kratzschmar J, Seidel H, Wolk K, Schonbein C, Schutt S, Friedrich M, Docke WD, Asadullah K, Volk HD, Grutz G. 2004. Expression profiling of IL-10-regulated genes in human monocytes and peripheral blood mononuclear cells from psoriatic patients during IL-10 therapy. Eur J Immunol 34: 481-93
  • Schroder M, Meisel C, Buhl K, Profanter N, Sievert N, Volk HD, Grutz G. 2003. Different Modes of IL-10 and TGF-beta to Inhibit Cytokine-Dependent IFN-gamma Production: Consequences for Reversal of Lipopolysaccharide Desensitization. J Immunol 170: 5260-7
  • Volk H, Asadullah K, Gallagher G, Sabat R, Grutz G. 2001. IL-10 and its homologs: important immune mediators and emerging immunotherapeutic targets. Trends Immunol 22: 414-7
  • Grutz GG, Bucher K, Lavenir I, Larson T, Larson R, Rabbitts TH. 1998. The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells. Embo J 17: 4594-605
  • Grutz G, Forster A, Rabbitts TH. 1998. Identification of the LMO4 gene encoding an interaction partner of the LIM-binding protein LDB1/NLI1: a candidate for displacement by LMO proteins in T cell acute leukaemia. Oncogene 17: 2799-803
  • Sanchez-Garcia I, Grutz G. 1995. Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2. Proc Natl Acad Sci U S A 92: 5287-91

Contact details

PD Dr. rer. nat. Gerald Grütz

t: +49 30 450 524 250
f: +49 30 450 524 962