Auswahl unserer Publikationen

  • Chiu JC, Vanselow JT, Kramer A, Edery I. (2008) The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock. Genes Dev. 2008 Jul 1;22(13):1758-72.
  • Locke JC, Westermark PO, Kramer A, Herzel H. (2008) Global parameter search reveals design principles of the mammalian circadian clock. BMC Syst Biol. 2008 Feb 29;2(1):22.
  • Brown SA, Kunz D, Dumas A, Westermark PO, Vanselow K, Tilmann-Wahnschaffe A, Herzel H, Kramer A (2008) Molecular insights into human daily behavior. PNAS. 2008 Feb 5;105(5):1602-7.
  • Vanselow K, Kramer A. (2007) Role of phosphorylation in the mammalian circadian clock. Cold Spring Harb Symp Quant Biol. 2007;72:167-76.
  • Bozek K, Kielbasa SM, Kramer A, Herzel H. (2007) Promoter analysis of Mammalian clock controlled genes. Genome Inform. 2007;18:65-74.
  • Schlosser A, Vanselow JT, Kramer A (2007) Comprehensive Phosphorylation Site Analysis of Individual Phosphoproteins Applying Scoring Schemes for MS/MS Data. Anal Chem. 2007 Oct 1;79(19):7439-49.
  • Reischl S, Vanselow K, Westermark PO, Thierfelder N, Maier B, Herzel H, Kramer A (2007). ß-TrCP1 mediated degradation of PERIOD2 is essential for circadian dynamics. J Biol Rhythms. 2007 Oct;22(5):375-86.
  • Bernard S, Gonze D, Cajavec B, Herzel H, Kramer A (2007) Synchronization-Induced Rhythmicity of Circadian Oscillators in the Suprachiasmatic Nucleus. Plos Comput Biol. 2007 Apr 13;3(4):e68.
  • Zhao W-N, Malinin N, Yang F-C, Staknis D, Gekakis N, Maier B, Reischl S, Kramer A, Weitz CJ (2007) CIPC is a mammalian circadian clock protein without invertebrate homologs. Nature Cell Biol. 2007 Mar;9(3):268-75.
  • Vanselow K, Vanselow JT, Westermark PO, Reischl S, Maier B, Korte T, Herrmann A, Herzel H, Schlosser A, Kramer A. (2006). Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS). Genes Dev. 20(19):2660-72.
  • Schlosser A, Vanselow JT, Kramer A. (2005). Mapping of phosphorylation sites by a multi-protease approach with specific phosphopeptide enrichment and NanoLC-MS/MS analysis.
  • Anal Chem. 77(16):5243-50.
  • Gonze D, Bernard S, Waltermann C, Kramer A, Herzel H. (2005). Spontaneous synchronization of coupled circadian oscillators. Biophys J. 89(1):120-9.
  • Geier, F., Becker-Weimann, S., Kramer, A. and Herzel, H. (2005). Entrainment in a model of the mammalian circadian oscillator.
  • J Biol Rhythms. 20(1):83-93.
  • Kramer, A., Yang, F.-C., Kraves, S. and Weitz, C. J. (2004).A screen for secreted factors of the suprachiasmatic nucleus.Methods Enzymol. 2005;393:645-63.
  • Becker-Weimann, S., Wolf, J., Herzel, H., and Kramer, A. (2004). Modeling feedback loops of the mammalian circadian oscillator. strong>Biophys J. 87(5):3023-34.
  • Kramer, A., Yang, F.-C., Snodgrass, P., Li, X.-D., Scammel, T. E.,Davis, F. and Weitz, C. J. (2001). Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling. Science. 294, 2511-2515.

Ausgewählte Publikationen anderer Forschungsbereiche

  • Portwich M, Keller S, Strauss HM, Mahrenholz CC, Kretzschmar I, Kramer A, Volkmer R (2007). A network of coiled-coil associations derived from synthetic GCN4 leucine zipper arrays. Angewandte Chemie Int Ed. 2007;46(10):1654-7.
  • Hoffmüller U., Knaute T., Hahn M., Höhne W., Schneider-Mergener J., Kramer A. (2000). Evolutionary transition pathways for changing peptide ligand specificity and structure. EMBO J. 19, 4866-4874.
  • Maier, B., Molinger, M., Cope, A. P., Fugger, L., Schneider-Mergener, J., Sønderstrup, G., Kamradt, T., and Kramer, A. (2000). Multiple cross-reactive self-ligands for Borrelia burgdorferi-specific HLA-DR4-restricted T cells. Eur J Immunol. 30, 448-457.
  • Winkler, K., Kramer, A., Küttner, G., Seifert, M., Scholz, C., Wessner, H. Schneider-Mergener, J. and Höhne, W. (2000). Changing the antigen binding specificity by single point mutations of an anti-p24 (HIV-1) antibody. J Immunol. 165, 4506-4514.
  • Kramer, A. and Schneider-Mergener, J. (1998). Synthesis and application of peptide libraries bound to continuous cellulose membranes. Meth Mol Biol. 87, 25-39.
  • Kramer, A., Keitel, T., Höhne, W. and Schneider-Mergener, J. (1997). Molecular basis of the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody. Cell. 91, 799-809.
  • Keitel, T., Kramer, A., Wessner, H., Scholz, C., Schneider-Mergener, J. and Höhne, W. (1997). Crystallographic analysis of of an anti-p24 (HIV-1) monoclonal antibody cross reactivity and polyspecificity. Cell. 91, 811-820.

Kontakt AG Kramer

Prof. Dr.
Achim Kramer

Sekretariat:
Annette Hayungs

Charité – Universitätsmedizin Berlin
Campus Charité Mitte
Chronobiologie
im CharitéCrossOver (CCO)
Virchowweg 6

Postanschrift:
Charitéplatz 1
10117 Berlin

t: +49 30 450 524 092

E-Mail

Forschungsdatenbank

Für mehr Details nutzen Sie bitte auch die Öffnet externen Link im aktuellen FensterForschungsdatenbank der Charité.

Kontakt IMI

Direktor:
Prof. Dr. Hans-Dieter Volk

Sekretariat:
Andrea Gorgas

Charité – Universitätsmedizin Berlin
Campus Virchow-Klinikum
Institutsgebäude Süd
Föhrer Str. 15 / Südstr. 2
13353 Berlin

Postanschrift:
Augustenburger Platz 1

t: +49 30 450 524 062
f: +49 30 450 524 932

E-Mail